This article was supported by Regione Veneto, Ricerca Sanitaria Finalizzata; Fondazione G Berlucchi per la Ricerca sul Cancro; Fondazione Cassa di Risparmio di Verona, Vicenza, Belluno e Ancona and ...
Researchers from TMDU find that CD22 restores B cell function in B cell receptor (BCR) signaling deficiencies by interacting with cis-ligands and upregulating BCR expression, thereby paradoxically ...
The KLHL14 gene acquires frequent inactivating mutations in mature B cell malignancies, especially in the MYD88L265P, CD79B mutant (MCD) genetic subtype of diffuse large B cell lymphoma (DLBCL), which ...
The rules to the kids' game "red light, green light" are easy to follow: red always means stop, and green always means go. But now, researchers from Japan have found that a key protein involved in B ...
Researchers from Osaka University find that the tyrosine kinase Csk inhibits germinal center B cell signaling, thereby decreasing the production of reactive oxygen species and apoptosis, and promoting ...
Overall survival in patients with Hodgkin lymphoma: Disparities by insurance status. This is an ASCO Meeting Abstract from the 2015 ASCO Annual Meeting I. This abstract does not include a full text ...
Cancer cells rely on different signaling pathways to promote their survival. Now, scientists at the University of Alberta have promising preclinical evidence that a new drug could work in blood ...
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) is an important factor from a complex downstream of Bruton tyrosine kinase (BTK) in the B-cell receptor (BCR) signaling ...
The prominent role of the BCR signaling in promoting B-CLL cell survival has prompted new therapeutic strategies targeted to signalosome elements. In particular, the most advanced BCR-signaling ...
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