Calorie restriction (CR) improves health, reduces cancer incidence and extends lifespan in multiple organisms including mice. CR was shown to enhance base excision repair and nucleotide excision ...

Enzymes that cut DNA at specific sites are called endonucleases; these enzymes play many roles in genomic replication, fidelity, and defense. The initial discovery of restriction endonucleases in the ...

In a recent letter published in Nature Aging, researchers assessed the impact of caloric restriction (CR) on biological aging among the comprehensive assessment of the long-term effects of reducing ...

Caloric restriction is a dietary intervention that is considered to be a reduction in the total energy intake with the maintenance of proper nutrition. It is associated with several health effects, ...