Despite the diversity inherent to cancer, they all share a common theme: many things tend to go wrong. This can make it difficult to understand which factors are driving the cancer and which ones are ...

A method for parallel sequencing of single-cell extrachromosomal circular DNA (ecDNA) and full-length mRNA transcriptomes has enabled new insights into the roles of ecDNA in cancer progression, ...

This is a preview. Log in through your library . Abstract Extrachromosomal circular DNA (eccDNA) originates from linear chromosomal DNA in various human tissues under physiological and disease ...

Howard Chang wasn’t looking for a change from his job at Stanford, where he worked as both a genomic researcher and a dermatologist. His busy lab there was focused on understanding how regulatory ...

Researchers including those at the University of Tokyo have made a surprising discovery hiding in people's mouths: Inocles, giant DNA elements that had previously escaped detection. These appear to ...