In the early 1960s, Mack Fulwyler joined the lab of Marvin Van Dilla at the Los Alamos National Laboratory as an engineer to study the effect of fallout radiation from nuclear weapons testing on ...
Flow cytometry, invented in the 1950s, uses antibodies linked to fluorescent probes to detect cell surface and intracellular proteins. Although able to achieve single-cell sensitivity, the method is ...
As for many antibody-based experiments, labeling challenges related to brightness, signal stability, target detection, and background noise are common roadblocks in flow cytometry. Scientists can ...