To compare matrix metalloproteinase (MMP) localisation in anterior keratectomy (AK) and lamellar keratectomy (LK) wounds. After an AK wound MMP-1 was present at the leading edge of migrating ...

Following cutaneous injury, the damaged dermal matrix is replaced by activated fibroblasts, which migrate from the surrounding stroma into the wound space in a process mediated by the binding of ...

Scientists have demonstrated that matrix metalloproteinases (MMPs) are instrumental in wound healing. A group led by Dr. Yasunori Okada at Keio University in Tokyo, Japan has demonstrated that matrix ...

Researchers at the University of Notre Dame have reported they were able to accelerate diabetic wound healing through a combination of inhibiting one matrix metalloproteinase (MMP), and that the wound ...

Each year, tens of thousands of people with diabetes in the U.S. have a lower limb amputated because a small foot wound failed to heal. With diabetes rates on the rise, scientists are eagerly ...

MMPs, especially MMP-1, are involved in the movement of new cells to a wound site. Researchers have found how thymosin beta 4 (TB4) hastens wound healing in the cornea. TB4 increases MMP-1 levels in ...

Non-healing chronic wounds are a major complication of diabetes, which result in more than 70,000 lower-limb amputations in the United States alone each year. The reasons why diabetic wounds are ...

A compound that accelerates diabetic wound healing has been identified by investigators, which may open the door to new treatment strategies. University of Notre Dame researchers have discovered a ...

Scientists at the Icahn School of Medicine at Mount Sinai report that a key protein may represent a novel way to use the immune system to speed healing and counter inflammatory, infectious, and ...

University of Notre Dame researchers have, for the first time, identified the enzymes that are detrimental to diabetic wound healing and those that are beneficial to repair the wound. There are ...

University of Notre Dame researchers have discovered a compound that accelerates diabetic wound healing, which may open the door to new treatment strategies. Non-healing chronic wounds are a major ...