We are entering into an exciting era of genomics where truly complete, high-quality assemblies of human chromosomes are available end-to-end, or from ‘telomere-to-telomere’ (T2T). Recently, the ...

Telomerase is essential for continuous cellular proliferation. Substantial insights have come from studies of budding yeast telomerase, which consists of a catalytic core in association with two ...

Scientists now know what an enzyme important in aging and cancer really looks like. A new study, published Wednesday in Nature, describes the structure of telomerase in more detail than has ever been ...

Maintenance of telomere stability is required for cells to escape from replicative senescence and proliferate indefinitely. Telomere length is maintained by a balance between processes that lengthen ...

Telomere shortening — a sign of cellular aging — is associated with multiple changes in the brain associated with dementia, whereas longer telomeres associate with better brain health and lower risk ...

Your DNA is located within the nuclei of your cells, where it’s bundled within structures called chromosomes. Each chromosome carries specific genetic information in the form of genes. As the cells in ...

Telomerase is present in 90% of human cancer cells and contributes significantly to proliferative abilities and immortality of cancer cells. MAIA Biotechnology is developing a Telomerase-Mediated ...

In participants receiving ateganosine as third-line therapy (n=22), the estimated median overall survival was 17.8 months. The Food and Drug Administration (FDA) has granted Fast Track Designation to ...