Before the safety and efficacy of a new vaccine can be evaluated in a Phase I clinical trial with human subjects, it must first undergo non-clinical safety evaluation in animal models. Regulatory ...

A review of studies carried out to assess the safety of industrial chemical substances has concluded that 11 substances—including certain metals, organic solvents, pesticides, and flame retardants—can ...

Survival, Durable Tumor Remission, and Long-Term Safety in Patients With Advanced Melanoma Receiving Nivolumab Fluourouracil (FU) is a mainstay of chemotherapy, although toxicities are common. Genetic ...

A cohort study of 65 clinical trials in multiple myeloma found that toxic effects are often described with subjective terminology that may not reflect adverse event rates reported in the studies. A ...

Researchers from UC San Diego’s Scripps Institution of Oceanography and UCLA announced the creation of an engineered bacterium that has the ability to convert the toxic form of mercury present in ...